If called upon by God to do so, yes. The question is, would God ever call one of his children to “abandon” his family. No. Even if a man is called to missionary work to a place where his family cannot go, he still has to provide for them back home and the calling is rarely, if ever, permanent. I don’t know of a mission organization that would require such a thing. When Jesus told the crowd following him around, “If anyone comes to me and does not hate father and mother, wife and children, brothers and sisters—yes, even their own life—such a person cannot be my disciple. And whoever does not carry their cross and follow me cannot be my disciple.” Luke 14:26–27 He does not mean here to “hate” as we understand it, for this would violate the second greatest commandment, to love our neighbor as ourselves; no, the Greek is: “miséō – properly, to detest (on a comparative basis); hence, denounce; to love someone or something less than someone (something) else, i.e. to renounce one choice in favor of another.”3404. μισέω (miseó) — to hate
It is to be our commitment that we WILL “forsake all others” for the sake of Christ and in obedience to him, but the specifics of what this might mean to the individual are personal, for example: “For there are eunuchs who were born that way, and there are eunuchs who have been made eunuchs by others–and there are those who choose to live like eunuchs for the sake of the kingdom of heaven. The one who can accept this should accept it.” Matthew 19:12
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